If you’re craving a rich and indulgent pasta dish, look no further than Seafood Alfredo Manicotti. This baked pasta masterpiece is filled with a delicious blend of shrimp, crab, and scallops, wrapped in cheesy ricotta filling, and smothered in a creamy Alfredo sauce. It’s the ultimate comfort food, perfect for seafood lovers and pasta enthusiasts alike.
Unlike traditional manicotti, which is often served with marinara sauce, this version swaps the red sauce for a velvety, garlicky Alfredo sauce that pairs beautifully with seafood.
Whether you’re making this dish for a special occasion or a cozy dinner, it’s guaranteed to impress. Plus, it’s easy to prepare in advance, making it a stress-free option for entertaining guests.
The Origins of Manicotti and Alfredo Sauce
What is Manicotti?
The word manicotti means “little sleeves” in Italian, referring to the tube-shaped pasta shells designed for stuffing. Traditionally, manicotti is filled with ricotta cheese and herbs, then baked in a tomato-based sauce. However, over time, chefs have experimented with various fillings and sauces, leading to the creation of seafood-based versions.
The Story Behind Alfredo Sauce
Alfredo sauce, originally from Rome, Italy, was created by Alfredo di Lelio in the early 1900s. His simple yet rich sauce combined butter, Parmesan cheese, and pasta water, resulting in a creamy texture that became a favorite worldwide. Today, Alfredo sauce has evolved into a thicker version using heavy cream, making it perfect for baked pasta dishes like Seafood Alfredo Manicotti.
How Seafood Became a Popular Manicotti Filling
Seafood has long been a staple in Italian and Mediterranean cuisine. The natural sweetness of shrimp, crab, and scallops complements the richness of Alfredo sauce, making it a luxurious twist on classic manicotti. By using seafood instead of traditional meat fillings, this dish becomes lighter yet incredibly flavorful.
Key Ingredients for the Perfect Seafood Alfredo Manicotti
1. Pasta Selection: Choosing the Right Shells
- Fresh vs. Dried Manicotti: Fresh pasta is more delicate, while dried manicotti is sturdier and easier to stuff.
- Alternative Options: If you can’t find manicotti, use cannelloni or rolled lasagna sheets instead.
2. Best Seafood for the Filling
Choosing the right seafood is key to getting the best flavor in Seafood Alfredo Manicotti. The most popular options include:
- Shrimp – Sweet and tender, perfect for pasta dishes.
- Crab – Adds a delicate, slightly briny taste.
- Scallops – Buttery and rich, giving the filling a smooth texture.
- Lobster (Optional) – A luxurious addition for a special touch.
Wondering which seafood mix works best for this dish? Check out this guide on everything you need to know about seafood mix to learn more about the best seafood combinations and how to prepare them for cooking.
Whether using fresh or frozen seafood, proper preparation is important. Be sure to thaw frozen seafood completely and pat it dry before mixing it into your filling to avoid excess moisture.
3. Crafting the Perfect Alfredo Sauce
- Traditional vs. Modern Alfredo: The original recipe uses only butter and Parmesan, but modern versions include heavy cream for extra richness.
- Dairy-Free Alternatives: Use cashew cream or coconut milk for a lighter option.
- Preventing a Curdled Sauce: Stir constantly and avoid high heat when making the sauce.
4. The Cheesy, Herby Goodness
- Ricotta Cheese – Forms the creamy base of the filling.
- Mozzarella & Parmesan – For gooey, melty goodness.
- Fresh Parsley & Basil – Adds a touch of herbaceous freshness.
Seafood Alfredo Manicotti Recipe
Ingredients
Manicotti
- 12 manicotti pasta shells
- 1 tablespoon salt (for boiling water)
- 1 tablespoon olive oil (to prevent sticking)
Seafood Filling
- 1 cup cooked shrimp, chopped
- 1/2 cup cooked lump crab meat
- 1/2 cup cooked scallops, chopped
- 1 ½ cups ricotta cheese
- 1/2 cup shredded mozzarella cheese
- 1/4 cup grated Parmesan cheese
- 1 large egg
- 2 tablespoons fresh parsley, chopped
- 1 teaspoon garlic powder
- 1 teaspoon onion powder
- 1/2 teaspoon salt
- 1/2 teaspoon black pepper
Alfredo Sauce
- 2 tablespoons unsalted butter
- 2 cloves garlic, minced
- 2 cups heavy cream
- 1 cup grated Parmesan cheese
- 1/2 teaspoon salt
- 1/2 teaspoon black pepper
- 1/4 teaspoon nutmeg (optional)
For Assembling & Baking
- 1/2 cup shredded mozzarella cheese (for topping)
- 1/4 cup grated Parmesan cheese (for topping)
- 2 tablespoons fresh parsley (for garnish)
Instructions
Step 1: Cook the Manicotti Pasta
- Bring a large pot of salted water to a rolling boil.
- Add the manicotti shells and cook according to package instructions until just al dente (about 6-7 minutes).
- Drain and rinse the pasta under cold water to stop cooking.
- Drizzle with olive oil to prevent sticking. Set aside.
Step 2: Prepare the Seafood Filling
- In a large bowl, combine chopped shrimp, crab, and scallops.
- Add ricotta, mozzarella, and Parmesan cheese.
- Mix in the egg, parsley, garlic powder, onion powder, salt, and black pepper.
- Stir well until the filling is fully combined.
✅ Pro Tip: If the filling is too dry, add 1-2 tablespoons of heavy cream for extra creaminess.
Step 3: Make the Alfredo Sauce
- In a medium saucepan, melt butter over medium heat.
- Add minced garlic and sauté for 1 minute until fragrant.
- Pour in heavy cream and stir continuously for 3-4 minutes.
- Gradually whisk in Parmesan cheese, stirring constantly until smooth.
- Season with salt, black pepper, and nutmeg (if using).
- Let the sauce simmer on low heat for 3-5 minutes, stirring occasionally.
✅ Pro Tip: If the sauce is too thick, add a splash of milk or chicken broth to adjust consistency.
Step 4: Assemble the Manicotti
- Preheat oven to 375°F (190°C).
- Spread 1/2 cup of Alfredo sauce on the bottom of a greased baking dish.
- Using a spoon or piping bag, fill each manicotti shell with the seafood mixture.
- Arrange the stuffed shells in the baking dish.
- Pour the remaining Alfredo sauce evenly over the shells.
- Sprinkle shredded mozzarella and Parmesan cheese on top.
Step 5: Bake & Serve
- Cover the baking dish with foil and bake for 20 minutes.
- Remove the foil and bake for another 10-15 minutes until the cheese is golden and bubbly.
- Let the dish rest for 5 minutes before serving.
- Garnish with fresh parsley and serve warm.
Serving Suggestions
- Pair with garlic bread or a fresh side salad.
- Serve with a light white wine (if applicable) or a refreshing lemon-infused sparkling water.
Storage & Reheating Tips
- Refrigeration: Store leftovers in an airtight container for up to 3 days.
- Freezing: Assemble the dish but do not bake. Freeze for up to 3 months. Thaw in the fridge overnight before baking.
- Reheating: Warm in the oven at 350°F (175°C) for 15 minutes, or microwave for 2 minutes.
Delicious Variations of Seafood Alfredo Manicotti
Love Seafood Alfredo Manicotti but want to try something new? There are so many ways to change up this dish while keeping the creamy, cheesy goodness. Below are some easy and tasty variations that bring exciting flavors and textures to your meal. Whether you want a spicy kick, a low-carb option, or extra veggies, there’s a version for you!
🔥 Spicy Cajun Seafood Alfredo Manicotti
If you enjoy bold, smoky flavors, this Cajun-style seafood pasta is a must-try!
- Add Cajun seasoning to the seafood mixture for a deep, spicy flavor.
- Use blackened shrimp instead of plain shrimp for extra heat.
- Mix in diced bell peppers and onions for a bit of crunch.
- Top with a dash of paprika for a warm, smoky taste.
👉 This version is great for those who love a little heat in their pasta!
🌱 Healthy & Low-Carb Seafood Alfredo Manicotti
Want a lighter version of this dish? Try these simple swaps!
- Use zucchini or eggplant slices instead of pasta shells.
- Swap heavy cream for Greek yogurt to cut calories.
- Reduce the cheese amount but keep Parmesan for flavor.
- Add extra spinach and mushrooms for more fiber and nutrients.
👉 This version keeps the creamy taste but makes it guilt-free!
🧀 Extra Cheesy Seafood Alfredo Manicotti
Are you a cheese lover? Make this dish even more indulgent!
- Use a mix of cheeses like Gouda, Fontina, and Asiago.
- Add a layer of ricotta cheese on top before baking.
- Sprinkle crispy Parmesan breadcrumbs for a crunchy finish.
- Double the mozzarella for an extra gooey texture.
👉 This variation is perfect for anyone who can’t get enough cheese!
🥦 Veggie-Packed Seafood Alfredo Manicotti
Want more greens in your meal? Load your manicotti with fresh vegetables!
- Add spinach, mushrooms, or zucchini to the seafood filling.
- Mix in finely chopped broccoli or bell peppers for extra texture.
- Use sun-dried tomatoes to add a slightly sweet and tangy flavor.
- Sprinkle fresh basil or parsley for a bright, herby finish.
👉 This version is perfect for veggie lovers and adds more nutrients to your dish!
🌿 Garlic Herb Seafood Alfredo Manicotti
Enhance the dish with fresh, aromatic herbs for a burst of flavor.
- Use fresh garlic, basil, and oregano in the Alfredo sauce.
- Mix in lemon zest for a fresh, zesty kick.
- Add rosemary and thyme for a more fragrant and earthy taste.
- Drizzle with truffle oil before serving for a gourmet touch.
👉 This version brings a fresh, vibrant flavor to the classic recipe!
🦞 Luxurious Lobster Seafood Alfredo Manicotti
Want to impress your guests? Add lobster for a restaurant-style dish!
- Replace shrimp and crab with lobster meat for a rich, buttery taste.
- Use white wine in the Alfredo sauce for extra depth of flavor.
- Garnish with fresh chives and lemon zest for a refined touch.
- Top with a small piece of lobster tail for a stunning presentation.
👉 This is the ultimate version for special occasions and celebrations!
Best Side Dishes to Serve with Seafood Alfredo Manicotti
A rich and creamy dish like Seafood Alfredo Manicotti pairs best with light, fresh, and flavorful sides. The right side dish can balance the richness of the pasta and add a satisfying crunch or refreshing contrast. Here are some of the best side dishes to serve with this delicious baked pasta!
🥖 Garlic Bread: A Classic Side for Seafood Alfredo Manicotti
Crunchy on the outside and soft on the inside, garlic bread is a must-have with creamy pasta.
- Brushed with butter and garlic, it adds a rich, savory taste.
- A crispy texture balances the smooth Alfredo sauce.
- Great for dipping, soaking up every drop of creamy goodness!
👉 For an extra twist, try cheesy garlic bread with mozzarella on top!
🥗 Fresh Salads: Light and Crisp with Seafood Alfredo Manicotti
A fresh salad helps cut through the richness of the Alfredo sauce.
- Caesar Salad – Crisp romaine, Parmesan, and crunchy croutons add a great texture.
- Arugula & Tomato Salad – A peppery bite with a light vinaigrette makes a great contrast.
- Caprese Salad – Juicy tomatoes, mozzarella, and fresh basil bring a refreshing taste.
👉 A drizzle of balsamic glaze makes any salad even better!
🥦 Roasted or Steamed Vegetables: A Healthy Side for Seafood Alfredo Manicotti
Adding veggies brings color, nutrients, and a fresh flavor to your meal.
- Steamed asparagus – A simple yet elegant pairing.
- Roasted Brussels sprouts – A slightly crispy, caramelized option.
- Sautéed spinach with garlic – Light, flavorful, and quick to prepare.
👉 Vegetables add a nice contrast without overpowering the main dish!
🍲 Light Soups: A Warm and Comforting Pairing
A light soup makes a great starter before digging into the pasta.
- Tomato Basil Soup – A slightly tangy flavor complements the rich Alfredo.
- Minestrone Soup – A veggie-packed option for a heartier meal.
- Lemon Chicken Soup – A bright, refreshing choice with a citrusy touch.
👉 A small bowl of soup warms you up without making the meal too heavy!
Common Mistakes and Pro Tips for Perfect Seafood Alfredo Manicotti
Even the best recipes can go wrong without the right technique. Avoid these common mistakes and follow these pro tips to make your Seafood Alfredo Manicotti perfect every time!
🚫 Overcooking the Seafood
Seafood cooks fast! Overcooked shrimp, crab, or scallops can turn rubbery.
✔ Pro Tip: Cook seafood just until opaque, then remove it from heat. It will finish cooking in the oven.
🚫 Breaking the Manicotti Shells
Manicotti shells are fragile and can crack if handled roughly.
✔ Pro Tip: Cook them until al dente and fill them carefully using a spoon or piping bag.
🚫 Alfredo Sauce Turning Too Thick or Lumpy
Too much heat can cause the sauce to thicken too much or even curdle.
✔ Pro Tip: Stir constantly over low to medium heat and add a splash of milk if needed.
🚫 Making the Dish Too Heavy
Too much cheese or sauce can make the dish feel too rich.
✔ Pro Tip: Balance flavors by adding fresh herbs, lemon zest, or a light salad on the side.
By avoiding these mistakes and using these simple pro tips, your Seafood Alfredo Manicotti will turn out creamy, flavorful, and perfectly cooked every time! 🍽️✨
Storing and Reheating Seafood Alfredo Manicotti Leftovers
Got leftovers? Seafood Alfredo Manicotti tastes just as good the next day if stored and reheated correctly. Follow these easy tips to keep it fresh and delicious!
🧊 How to Store Seafood Alfredo Manicotti
Keeping leftovers fresh is key! Here’s how:
- Refrigerate: Place leftovers in an airtight container and store for up to 3 days.
- Freeze: Wrap the dish tightly in foil or place it in a freezer-safe container. It stays good for up to 3 months.
👉 For best results, freeze before baking. Then, bake fresh when ready to eat!
🔥 Best Way to Reheat Seafood Alfredo Manicotti
Reheating correctly keeps the pasta creamy and soft.
- Oven (Best Method): Bake at 350°F (175°C) for 15–20 minutes. Cover with foil to keep it from drying out.
- Microwave: Heat in 30-second bursts, stirring in between to keep the sauce smooth.
- Stovetop: Warm over low heat with a splash of milk or cream to restore creaminess.
👉 Avoid high heat it can make the sauce separate!
With these simple storage and reheating tips, your Seafood Alfredo Manicotti will taste fresh and creamy every time! 🍽️✨
FAQs: Answering Common Questions
Can I make this dish ahead of time?
Yes! Assemble it up to 24 hours in advance and refrigerate before baking.
What seafood works best?
Shrimp, crab, and scallops are ideal, but lobster is a great upgrade!
Can I use store-bought Alfredo sauce?
Yes, but homemade sauce delivers the best flavor.
Final Thoughts
Seafood Alfredo Manicotti is creamy, cheesy, and full of flavor. Whether for a family dinner or a special occasion, it’s guaranteed to be a hit. Try it out and enjoy a restaurant-quality dish at home! 🍽️✨